NADPH Oxidase 4 Antikörper (AA 81-180) (AbBy Fluor® 750)
Kurzübersicht für NADPH Oxidase 4 Antikörper (AA 81-180) (AbBy Fluor® 750) (ABIN5007261)
Target
Alle NADPH Oxidase 4 (NOX4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 81-180
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Dog,Cow,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from mouse Nox-4
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Isotyp
- IgG
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Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- NADPH Oxidase 4 (NOX4)
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Andere Bezeichnung
- NADPH oxidase 4
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Hintergrund
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Synonyms: AI64821, NADPH oxidase 4, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase, Superoxide-generating NADPH oxidase 4, Nox4, Renox
Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
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Gen-ID
- 50490
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UniProt
- Q9JHI8
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Pathways
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
Target
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