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MYBPC3 Antikörper (AbBy Fluor® 750)

Der Kaninchen Polyklonal Anti-MYBPC3-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, MYBPC3 in Proben von Human, Ratte und Maus zu detektieren.
Produktnummer ABIN5007175

Kurzübersicht für MYBPC3 Antikörper (AbBy Fluor® 750) (ABIN5007175)

Target

Alle MYBPC3 Antikörper anzeigen
MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Reaktivität

  • 39
  • 33
  • 25
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 50
  • 2
  • 2
Kaninchen

Klonalität

  • 52
  • 2
Polyklonal

Konjugat

  • 27
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MYBPC3 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation

  • 44
  • 23
  • 22
  • 12
  • 6
  • 5
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human MYBPC3

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

    Andere Bezeichnung

    MYBPC3

    Hintergrund

    Synonyms: C protein cardiac muscle isoform, cardiac muscle isoform, cardiac-type, C-protein, Cardiac MyBP C, Cardiac MyBP-C, Cardiac myosin binding protein C, MYBP C, MYBPC, MYBPC3, Myosin binding protein C cardiac, Myosin binding protein C cardiac-type, Myosin-binding protein C, MYPC3_HUMAN.

    Background: MYBPC3 encodes the cardiac isoform of the thick-filament myosin-binding protein C. It is found in the crossbridge-bearing zone (C region) of A bands in vertebrate striated muscle. Regulatory phosphorylation of MYBPC3 by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. MYBPC3 binds F-Actin, MHC and native thin filaments, and modifies the activity of Actin-activated myosin ATPase. Mutations in the MYBPC3 gene lead mainly to truncation of the protein, which results in one cause of familial hypertrophic cardiomyopathy type 4 (CMH4), a heart disorder characterized by ventricular hypertrophy, which often involves the interventricular septum and is usually asymmetric. The MYBPC3 gene maps to chromosome 11p11.2.

    Gen-ID

    4607
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