LY86 Antikörper (AA 65-162) (AbBy Fluor® 680)

Produktnummer ABIN5006659

Der Kaninchen Polyklonal Anti-LY86-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, LY86 in Proben von Ratte zu detektieren.

Kurzübersicht für LY86 Antikörper (AA 65-162) (AbBy Fluor® 680) (ABIN5006659)

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LY86 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-LY86 Antikörper (AbBy Fluor® 680)

Bindungsspezifität: AA 65-162

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LY-86

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LY86

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Andere Bezeichnung: MD1

Hintergrund:

Synonyms: BPAD, dJ80N2.1, LY86, LY-86, LY 86, Lymphocyte antigen 86, Lymphocyte antigen 86 precursor, Major affective disorder 1, MD-1, MD1, MD 1, MD1 protein, MD1 RP105 associated, MD1 RP105 associated, MMD-1, RP1-80N2.1.

Background: MD1 is a 28 kDa molecule that is associated at the cell surface with RP105 (CD180). RP105 is a leucine-rich repeat (LRR) molecule that is expressed on B lymphocytes. It was first identified by a mAb that protects spleen B cells from irradiation-induced apoptosis. LRR proteins, such as Toll receptors, have a role in innate immunity. MD1 is primarily expressed by B cells, dendritic cells and monocytes, and promotes the recognition of, and subsequent signaling by LPS in the innate immune system. MD1 does not have any homology to other molecules. MD1 when expressed alone behaves as a secretory protein. Expression of MD1 in a cell increases the expression of RP105.

Gen-ID: 9450

Pathways: Toll-Like Receptors Cascades