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PD-1 Antikörper (C-Term)

Name: PD-1 Antikörper (C-Term)
SKU: ABIN500457
Price: 856.31 EUR
Availability: InStock

PDCD1 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of PD-1 in THP-1 cell lysate with AP30650PU-N PD1 antibody at 1 μg/ml in the (A) absence and (B) presence of blocking peptide. (PD-1 Antikörper (C-Term))

Immunohistochemistry of PD-1 in Human brain tissue with AP30650PU-N PD1 antibody at 2. (PD-1 Antikörper (C-Term))

IHC (p)

2 Abbildungen

Produktnummer ABIN500457

Datenblatt (PDF)

Target Alle PD-1 (PDCD1) Antikörper anzeigen

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
Bindungsspezifität
16

8

5

5

4

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
140

85

24

5

3

1
Human, Maus, Ratte
Wirt
74

70

35

12

9

3

2
Kaninchen
Passende Sekundärantikörper
Klonalität
147

55

2
Polyklonal
Konjugat
95

16

13

11

7

6

5

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser PD-1 Antikörper ist unkonjugiert
Applikation
132

56

45

39

37

17

13

13

13

12

10

10

10

8

6

4

4

4

4

3

3

2

2

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität

This antibody detects CD279 / PD1 at C-term.

Aufreinigung

Peptide Affinity Chromatography

Immunogen

PD-1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of Human PD-1.

Isotyp

IgG

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Applikationshinweise

ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

Store the antibody at 2-8 °C
Target

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung

CD279 / PD1 (PDCD1 Produkte)

Synonyme

CD279 antikoerper, PD-1 antikoerper, PD1 antikoerper, SLEB2 antikoerper, hPD-1 antikoerper, hPD-l antikoerper, Ly101 antikoerper, Pdc1 antikoerper, programmed cell death 1 antikoerper, PDCD1 antikoerper, Pdcd1 antikoerper

Hintergrund

Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1

Gen-ID

5133

UniProt

Q15116

Pathways

Cancer Immune Checkpoints