IL21 Receptor Antikörper (Extracellular Domain)

Produktnummer ABIN499988

Der Kaninchen Polyklonal Anti-IL21 Receptor-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, IL21 Receptor in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für IL21 Receptor Antikörper (Extracellular Domain) (ABIN499988)

Target: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL21 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-IL21 Receptor Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: IL-21 receptor antibody was raised against a synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Human IL-21 Receptor (Extracellular Domain) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 60 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu IL21 Receptor

Target: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Andere Bezeichnung: Interleukin-21 Receptor / IL21R

Hintergrund: A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21 . The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.Synonyms: IL-21R, IL21 receptor, NILR, Novel interleukin receptor

Gen-ID: 50615

NCBI Accession: NP_068570

UniProt: Q9HBE5

Pathways: JAK-STAT Signalweg