Apolipoprotein C-II Antikörper (AA 31-101) (AbBy Fluor® 750)

Produktnummer ABIN4996734

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Apolipoprotein C-II in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Apolipoprotein C-II Antikörper (AA 31-101) (AbBy Fluor® 750) (ABIN4996734)

Target: Apolipoprotein C-II (APOC2)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Apolipoprotein C-II Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Apolipoprotein C-II Antikörper (AbBy Fluor® 750)

Bindungsspezifität: AA 31-101

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Apolipoprotein CII/APOC2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Apolipoprotein C-II

Target: Apolipoprotein C-II (APOC2)

Andere Bezeichnung: APOC2

Hintergrund:

Synonyms: APC 2, APC2, Apo CII, APOC 2, ApoC II, apoC-II ,APOC2, APOC2 protein, ApoCII, Apolipoprotein C II, Apolipoprotein C II precursor, ApolipoproteinCII, MGC75082,

Background: Apolipoproteins are protein components of plasma lipoproteins (1). The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins (2). The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages (3,4). The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues (57). The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase (8). The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver (9,10).

Gen-ID: 344

Pathways: Lipid Metabolism