Adenylosuccinate Lyase Antikörper (AA 185-280) (AbBy Fluor® 680)

Produktnummer ABIN4996123

Der Kaninchen Polyklonal Anti-Adenylosuccinate Lyase-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, Adenylosuccinate Lyase in Proben von Human und Maus zu detektieren.

Kurzübersicht für Adenylosuccinate Lyase Antikörper (AA 185-280) (AbBy Fluor® 680) (ABIN4996123)

Target: Adenylosuccinate Lyase (ADSL)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenylosuccinate Lyase Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Adenylosuccinate Lyase Antikörper (AbBy Fluor® 680)

Bindungsspezifität: AA 185-280

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adenylosuccinate Lyase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Adenylosuccinate Lyase

Target: Adenylosuccinate Lyase (ADSL)

Andere Bezeichnung: Adenylosuccinate Lyase

Hintergrund:

Synonyms: Adenylosuccinase, Adenylosuccinate lyase, ADSL, AMPS, ASase, ASL, PUR8_HUMAN.

Background: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Pathways: Ribonucleoside Biosynthetic Process