C9 Antikörper

Produktnummer ABIN499053

Der Kaninchen Polyklonal anti-C9 Antikörper (ABIN499053) detektiert spezifisch C9 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für C9 Antikörper (ABIN499053)

Target: C9 (Complement Component C9 (C9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-C9 Antikörper

Spezifität: This antibody detects endogenous levels of C9 protein. (region surrounding His216)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu C9

Target: C9 (Complement Component C9 (C9))

Andere Bezeichnung: Complement C9

Hintergrund: C9 is synthesised in the liver and monocytes, and is a plasma protein consisting of a single polypeptide chain of molecular weight 71 kDa. Normal plasma concentration is 60 mg/L. C9 forms part of the membrane attack complex (MAC) the cytolytic terminal complex of the complement pathways. C9 binds to the membrane associated C5b-8, binding of C9 to C5b-8 leads to the circular polymerisation of 12-18 C9 Molecules. This is the basis of the hydrophilic, proteinwalled, trans-membrane channel formed by the MAC, which leads to cell lysis and destruction.Synonyms: Complement 9, Complement component C9

Molekulargewicht: approx. 70 kDa

Gen-ID: 735

NCBI Accession: NP_001728

UniProt: P02748

Pathways: Komplementsystem