Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
MAY1 antikoerper, PKCD antikoerper, nPKC-delta antikoerper, AI385711 antikoerper, D14Ertd420e antikoerper, PKC[d] antikoerper, PKCdelta antikoerper, Pkcd antikoerper, fb09d10 antikoerper, fv43b11 antikoerper, prkcd antikoerper, wu:fb09d10 antikoerper, wu:fv43b11 antikoerper, zgc:56558 antikoerper, PKC-delta antikoerper, may1 antikoerper, npkc-delta antikoerper, pkc-delta2 antikoerper, pkcd antikoerper, tpa-1 antikoerper, protein kinase C delta antikoerper, protein kinase C, delta antikoerper, protein kinase C, delta a antikoerper, protein kinase C delta L homeolog antikoerper, PRKCD antikoerper, Prkcd antikoerper, prkcda antikoerper, prkcd.L antikoerper, prkcd antikoerper
Hintergrund
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (alpha, betaI, betaII and gamma) and novel (n) PKC isoforms (delta, epsilon, zeta, eta and theta). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and epsilon are independent of Ca2+. On the other hand, nPKC delta and epsilon, as well as all of the cPKC members, possess phorbol esterbinding activities and kinase activities.Synonyms: PKC delta, PKC-delta, PKCD, Protein kinase C delta type