PKC epsilon Antikörper

Produktnummer ABIN498251

Der Kaninchen Polyklonal anti-PKC epsilon Antikörper wird verwendet zum Nachweis von PKC epsilon in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für PKC epsilon Antikörper (ABIN498251)

Target: PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC epsilon Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PKC epsilon Antikörper

Spezifität: This antibody detects endogenous levels of PKC ε protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu PKC epsilon

Target: PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Andere Bezeichnung: PRKCE

Hintergrund: Members of the protein kinase C family fall into three categories: conventional (PKC alph,a beta I, beta II, gamma), novel (delt,a epsilon, et,a mu, theta), and atypical (lamd,a zeta). Conventional PKC isoforms are dependent on calcium and diacylglycerol (DAG) for their activity, whereas novel PKC isoforms are calcium dependent, and atypical PKC isoforms are calcium and DAG independent.Synonyms: PKC epsilon, PKC-epsilon, PKCE, Protein kinase C epsilon type

Molekulargewicht: approx. 83 kDa

Gen-ID: 5581

NCBI Accession: NP_005391

UniProt: Q02156

Pathways: T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling