HDAC3 Antikörper

Produktnummer ABIN498133

Produktdetails anti-HDAC3 Antikörper

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of SMAP45 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu HDAC3

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Andere Bezeichnung: HDAC3 (HDAC3 Produkte)

Synonyme: CG2128 antikoerper, DHDAC3 antikoerper, DmHDAC3 antikoerper, Dmel\\CG2128 antikoerper, Dromel_CG2128_FBtr0078767_hdac3_mORF antikoerper, HDAC antikoerper, HDAC3 antikoerper, Hdac 3 antikoerper, dHDAC3 antikoerper, dmHDA402 antikoerper, hdac3 antikoerper, HDm antikoerper, hd3 antikoerper, RPD3 antikoerper, XRpd3 antikoerper, rpd3-2 antikoerper, HD3 antikoerper, RPD3-2 antikoerper, AW537363 antikoerper, zgc:55927 antikoerper, Histone deacetylase 3 antikoerper, histone deacetylase 3 antikoerper, histone deacetylase 3 S homeolog antikoerper, HDAC3 antikoerper, hdac3 antikoerper, CNL05260 antikoerper, Hdac3 antikoerper, hdac3.S antikoerper

Hintergrund: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone acetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.Synonyms: HD3, Histone deacetylase 3, RPD3-2, SMAP45

Molekulargewicht: approx. 50 kDa

Gen-ID: 8841

NCBI Accession: NP_003874

UniProt: O15379

Pathways: Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development