CSF1R Antikörper

Produktnummer ABIN498117

Produktdetails anti-CSF1R Antikörper

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSF1R Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of CSFR protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: Immunoflourescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-CSF1R Antikörper (ABIN498117)

Dekker, van Geemen, van den Bogaerdt, Driessen-Mol, Aikawa, Smits: "Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves." in: Frontiers in cardiovascular medicine, Vol. 5, pp. 105, (2018) (PubMed).

Details zu CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Andere Bezeichnung: CD115 (CSF1R Produkte)

Synonyme: AI323359 antikoerper, CD115 antikoerper, CSF-1R antikoerper, Csfmr antikoerper, Fim-2 antikoerper, Fms antikoerper, M-CSF-R antikoerper, M-CSFR antikoerper, C-FMS antikoerper, CSFR antikoerper, FIM2 antikoerper, FMS antikoerper, HDLS antikoerper, PDGFRB antikoerper, MGC89146 antikoerper, CSF-1-R antikoerper, c-fms antikoerper, mrfms antikoerper, CSF1 antikoerper, M-CSF antikoerper, csf1r antikoerper, fms antikoerper, panther antikoerper, colony stimulating factor 1 receptor antikoerper, macrophage colony-stimulating factor receptor antikoerper, colony stimulating factor 1 receptor, a antikoerper, Csf1r antikoerper, CSF1R antikoerper, m-csfr antikoerper, csf1r antikoerper, csf1ra antikoerper

Hintergrund: This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.Synonyms: CSF-1-R, CSF1R, FMS, Fms proto-oncogene, Macrophage colony-stimulating factor 1 receptor, c-fms

Molekulargewicht: approx. 92, 108 kDa

Gen-ID: 1436

NCBI Accession: NP_005202

UniProt: P07333

Pathways: RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization