TTC8 Antikörper (Internal Region)

Produktnummer ABIN498031

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch TTC8 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus, Rind (Kuh), Hund und Schwein.

Kurzübersicht für TTC8 Antikörper (Internal Region) (ABIN498031)

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TTC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-TTC8 Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-KEVLKQDNTH VE

Spezifität: This antibody is expected to recognize all reported isoforms (NP_653197.2, NP_938051.1, NP_938052.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Canine (Dog), Bovine and Porcine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the Internal region of the protein sequence according to NP_653197.2, NP_938051.1, NP_938052.1.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit Dilution: 1/8000. Western blot: 0.2-0.6 μg/mL. Approx 60 kDa band observed in Human Testis lysates(calculated MW of 58.0 kDa according to NP_653197.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TTC8

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Andere Bezeichnung: TTC8 / BBS8

Hintergrund: Defects in TTC8 are the cause of Bardet-Biedl syndrome type 8 (BBS8). This is a genetically heterogeneous, autosomal recessive disorder and the primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.Synonyms: Bardet-Biedl syndrome 8 protein, TPR repeat protein 8, Tetratricopeptide repeat protein 8

Gen-ID: 123016

NCBI Accession: NP_653197

UniProt: Q8TAM2

Pathways: Hedgehog Signalweg