TTC8 Antikörper (AA 251-330) (Biotin)

Produktnummer ABIN1391695

Produktdetails anti-TTC8 Antikörper (Biotin)

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Bindungsspezifität: AA 251-330

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTC8 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BBS8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu TTC8

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Andere Bezeichnung: BBS8/TTC8 (TTC8 Produkte)

Synonyme: TTC8 antikoerper, bbs8 antikoerper, fk26c02 antikoerper, wu:fk26c02 antikoerper, zgc:136718 antikoerper, DKFZp459L2429 antikoerper, BBS8 antikoerper, RP51 antikoerper, 0610012F22Rik antikoerper, AV001447 antikoerper, tetratricopeptide repeat domain 8 antikoerper, TTC8 antikoerper, ttc8 antikoerper, lpa_01174 antikoerper, Ttc8 antikoerper

Hintergrund:

Synonyms: Bardet Biedl syndrome 8 protein, Bardet Biedl syndrome type 8, Bardet-Biedl syndrome 8 protein, BBS8, Tetratricopeptide repeat domain 8, Tetratricopeptide repeat protein 8, TPR repeat protein 8, TTC 8, Ttc8, TTC8_HUMAN.

Background: Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. BBS patients also have an increased risk of developing diabetes, hypertension, and congenital heart defects. BBS is a heterogeneous disorder mapping to eight genetic loci and encoding eight proteins, BBS1-BBS8. Five BBS proteins encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS2 contains two overlapping genes: BBS2L1 and BBS2L2. BBSL1 was re-named BBS7, whereas BBS2L2 independently funcitons as BBS1. BBS7 contains 672 amino acids and is expressed at low to moderate levels in most human tissues.

Pathways: Hedgehog Signalweg