VASP Antikörper (AA 267-296)

Produktnummer ABIN3029586

Dieses Anti-VASP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von VASP in WB, IHC und ELISA. Geeignet für Human.

Kurzübersicht für VASP Antikörper (AA 267-296) (ABIN3029586)

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-VASP Antikörper

Bindungsspezifität: AA 267-296

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 267-296 from the human protein was used as the immunogen for this VASP antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the VASP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the VASP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu VASP

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Andere Bezeichnung: VASP

Hintergrund: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

UniProt: P50552

Pathways: T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Tube Formation