Tuberin Antikörper (AA 1397-1426)
Kurzübersicht für Tuberin Antikörper (AA 1397-1426) (ABIN3029313)
Target
Alle Tuberin (TSC2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1397-1426
-
Verwendungszweck
- TSC2 Antibody
-
Aufreinigung
- Antigen affinity
-
Immunogen
- A portion of amino acids 1397-1426 from the human protein was used as the immunogen for this TSC2 antibody.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- Titration of the TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
-
Andere Bezeichnung
- TSC2
-
Hintergrund
- Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
-
UniProt
- P49815
-
Pathways
- RTK Signalweg, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
Target
-