Tuberin Antikörper (AA 900-1150)
Kurzübersicht für Tuberin Antikörper (AA 900-1150) (ABIN6149611)
Target
Alle Tuberin (TSC2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 900-1150
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Sequenz
- CRLPFRKDFV PFITKGLRSN VLLSFDDTPE KDSFRARSTS LNERPKSLRI ARPPKQGLNN SPPVKEFKES SAAEAFRCRS ISVSEHVVRS RIQTSLTSAS LGSADENSVA QADDSLKNLH LELTETCLDM MARYVFSNFT AVPKRSPVGE FLLAGGRTKT WLVGNKLVTV TTSVGTGTRS LLGLDSGELQ SGPESSSSPG VHVRQTKEAP AKLESQAGQQ VSRGARDRVR SMSGGHGLRV GALDVPASQF L
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 900-1150 of human TSC2 (NP_000539.2).
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Isotyp
- IgG
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anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibody
TSC2 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB13393 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1611-1807) antibodyTSC2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1601-1750) antibodyTSC2 Reaktivität: Human, Maus, Ratte ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) antibodyKD Validated TSC2 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB1120 unconjugated Recombinant Antibody
anti-Tuberous Sclerosis 2 (TSC2) antibodyKD Validated TSC2 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB1000 unconjugated Recombinant Antibody
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibodyTSC2 Reaktivität: Human ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibodyTSC2 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1397-1426) antibodyTSC2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB42388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pSer1387) antibodyTSC2 Reaktivität: Human DB, IF Wirt: Kaninchen Polyclonal RB11388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibodyTSC2 Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB13340 unconjugated
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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Andere Bezeichnung
- TSC2
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Hintergrund
- Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.,LAM,PPP1R160,TSC4,TSC2,Tuberin,tuberin,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,Akt downstream targets,Regulators,TSC2
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Molekulargewicht
- 25 kDa/187-200 kDa
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Gen-ID
- 7249
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UniProt
- P49815
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Pathways
- RTK Signalweg, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
Target
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