PLAT Antikörper (AA 371-399)

Produktnummer ABIN3032243

Der Kaninchen Polyklonal Anti-PLAT-Antikörper wurde für WB, ELISA, IHC und FACS validiert. Er ist geeignet, PLAT in Proben von Human zu detektieren.

Kurzübersicht für PLAT Antikörper (AA 371-399) (ABIN3032243)

Target: PLAT (Plasminogen Activator, Tissue (PLAT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-PLAT Antikörper

Bindungsspezifität: AA 371-399

Aufreinigung: Purified

Immunogen: A portion of amino acids 371-399 from the human protein was used as the immunogen for this tPA antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the tPA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the tPA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PLAT

Target: PLAT (Plasminogen Activator, Tissue (PLAT))

Andere Bezeichnung: TPA

Hintergrund: TPA is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism.

UniProt: P00750

Pathways: Autophagie, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interaktom