TLR8 Antikörper (AA 957-987)

Produktnummer ABIN3029181

Dieses Anti-TLR8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TLR8 in WB, IHC und ELISA. Geeignet für Human und Maus.

Kurzübersicht für TLR8 Antikörper (AA 957-987) (ABIN3029181)

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-TLR8 Antikörper

Bindungsspezifität: AA 957-987

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 957-987 from the mouse protein was used as the immunogen for this TLR8 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TLR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TLR8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TLR8

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Andere Bezeichnung: TLR8

Hintergrund: TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

UniProt: P58682

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades