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TBK1 Antikörper (AA 8-35)

TBK1 Reaktivität: Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029093
  • Target Alle TBK1 Antikörper anzeigen
    TBK1 (TANK-Binding Kinase 1 (TBK1))
    Bindungsspezifität
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 8-35
    Reaktivität
    • 75
    • 52
    • 28
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 71
    • 17
    • 1
    Kaninchen
    Klonalität
    • 70
    • 19
    Polyklonal
    Konjugat
    • 43
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Dieser TBK1 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 41
    • 25
    • 10
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 8-35 from the mouse protein was used as the immunogen for this Tbk1 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TBK1 Primärantikörper
  • Applikationshinweise
    Titration of the Tbk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the Tbk1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    TBK1 (TANK-Binding Kinase 1 (TBK1))
    Andere Bezeichnung
    Tbk1 (TBK1 Produkte)
    Synonyme
    nak antikoerper, t2k antikoerper, TBK1 antikoerper, wu:fk70c05 antikoerper, zgc:136548 antikoerper, NAK antikoerper, T2K antikoerper, 1200008B05Rik antikoerper, AI462036 antikoerper, AW048562 antikoerper, TANK binding kinase 1 L homeolog antikoerper, TANK binding kinase 1 antikoerper, TANK-binding kinase 1 antikoerper, tbk1.L antikoerper, TBK1 antikoerper, tbk1 antikoerper, Tbk1 antikoerper
    Hintergrund
    Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.
    UniProt
    Q9WUN2
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interaktom
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