TBK1 Antikörper (AA 8-35)

Produktnummer ABIN3029093

Der Kaninchen Polyklonal Anti-TBK1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, TBK1 in Proben von Maus zu detektieren.

Kurzübersicht für TBK1 Antikörper (AA 8-35) (ABIN3029093)

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TBK1 Antikörper

Bindungsspezifität: AA 8-35

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 8-35 from the mouse protein was used as the immunogen for this Tbk1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Tbk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Tbk1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TBK1

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Andere Bezeichnung: Tbk1

Hintergrund: Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.

UniProt: Q9WUN2

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interaktom