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SUV39H2 Antikörper (AA 367-395)

SUV39H2 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029053
  • Target Alle SUV39H2 Antikörper anzeigen
    SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 367-395
    Reaktivität
    • 59
    • 26
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 57
    • 2
    • 1
    Kaninchen
    Klonalität
    • 52
    • 8
    Polyklonal
    Konjugat
    • 31
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser SUV39H2 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 32
    • 23
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität (Details)
    Expected species reactivity: Mouse, Primate
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 367-395 from the human protein was used as the immunogen for this SUV39H2 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SUV39H2 Primärantikörper
  • Applikationshinweise
    Titration of the SUV39H2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the SUV39H2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
    Andere Bezeichnung
    SUV39H2 (KTM1B) (SUV39H2 Produkte)
    Hintergrund
    Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher order chromatin organization during spermatogenesis.
    UniProt
    Q9H5I1
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