NCOA1 Antikörper (AA 1338-1367)

Produktnummer ABIN3032057

Der Kaninchen Polyklonal Anti-NCOA1-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, NCOA1 in Proben von Human zu detektieren.

Kurzübersicht für NCOA1 Antikörper (AA 1338-1367) (ABIN3032057)

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-NCOA1 Antikörper

Bindungsspezifität: AA 1338-1367

Kreuzreaktivität (Details): Expected species reactivity: Pig

Aufreinigung: Purified

Immunogen: A portion of amino acids 1338-1367 from the human protein was used as the immunogen for this SRC-1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the SRC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SRC-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NCOA1

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Andere Bezeichnung: SRC-1

Hintergrund: SRC-1/NCOA1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. This protein binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion.

UniProt: Q15788

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha