Sonic Hedgehog Antikörper (N-Term)
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- Target Alle Sonic Hedgehog (SHH) Antikörper anzeigen
- Sonic Hedgehog (SHH)
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Bindungsspezifität
- N-Term
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Sonic Hedgehog Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antigen affinity purified
- Immunogen
- This mouse Shh antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 58-91 amino acids from the N-terminal region of mouse Sonic hedgehog.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SHH Primärantikörper
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anti-Sonic Hedgehog (SHH) (AA 21-120) antibody
SHH Reaktivität: Human, Maus, Ratte, Schwein WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 26-161) antibodySHH Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 5H4 unconjugated
anti-Sonic Hedgehog (SHH) (C-Term) antibodyVerified SHH Reaktivität: Human, Maus WB, ELISA, IF, FACS Wirt: Ziege Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (N-Term) antibodySHH Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Meerschweinchen, Pferd, Ziege, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 26-161) antibodySHH Reaktivität: Human, Maus, Affe WB, IHC, ELISA, FACS Wirt: Maus Monoclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 36-193) antibodySHH Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 36-193) antibodySHH Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal D6 unconjugated
anti-Sonic Hedgehog (SHH) (AA 58-91), (N-Term) antibodySHH Reaktivität: Human, Maus, Ratte WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB52387 unconjugated
anti-Sonic Hedgehog (SHH) (AA 24-197) antibodySHH Reaktivität: Human, Ratte, Hund, Affe WB, IF Wirt: Maus Monoclonal 10H6 unconjugated
anti-Sonic Hedgehog (SHH) (AA 237-399) antibodySHH Reaktivität: Ratte WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Titration of the Shh antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The 45 kDa precursor protein autocleaves into 27 kDa amino and 19 kDa carboxy fragments.\. Western blot: 1:1000-2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the Shh antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- Sonic Hedgehog (SHH)
- Andere Bezeichnung
- Shh (SHH Produkte)
- Hintergrund
- Sonic hedgehog intercellular signaling is essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO. [UniProt]
- UniProt
- Q62226
- Pathways
- Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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