Sonic Hedgehog Antikörper (AA 395-450)
Kurzübersicht für Sonic Hedgehog Antikörper (AA 395-450) (ABIN3029025)
Target
Alle Sonic Hedgehog (SHH) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 395-450
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 395-450 were used as immunogen for this Shh antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Titration of the Shh antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The 45 kDa precursor protein autocleaves into 27 kDa amino and 19 kDa carboxy fragments.\. Flow Cytometry: 1:25,Western blot: 1:1000 (1)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Shh antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Sonic Hedgehog (SHH)
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Andere Bezeichnung
- Shh
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Hintergrund
- Sonic hedgehog binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO.
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UniProt
- Q62226
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Pathways
- Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Target
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