RAD51C Antikörper (AA 169-198)

Produktnummer ABIN3032429

Der Kaninchen Polyklonal Anti-RAD51C-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, RAD51C in Proben von Human zu detektieren.

Kurzübersicht für RAD51C Antikörper (AA 169-198) (ABIN3032429)

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RAD51C Antikörper

Bindungsspezifität: AA 169-198

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 169-198 from the human protein was used as the immunogen for this RAD51C antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the RAD51C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RAD51C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu RAD51C

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Andere Bezeichnung: RAD51C

Hintergrund: This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

UniProt: O43502

Pathways: DNA Reparatur