Progesterone Receptor Antikörper (Isoform A)

Produktnummer ABIN3032310

Der Maus Monoklonal anti-Progesterone Receptor Antikörper (Klon 312CT8-2-1-6) (ABIN3032310) detektiert spezifisch Progesterone Receptor in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Progesterone Receptor Antikörper (Isoform A) (ABIN3032310)

Target: Progesterone Receptor (PGR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Progesterone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 312CT8-2-1-6

Produktdetails anti-Progesterone Receptor Antikörper

Bindungsspezifität: AA 349-377, Isoform A

Verwendungszweck: Progesterone Receptor Antibody / Isoform A & B

Aufreinigung: Purified

Immunogen: A portion of amino acids 349-377 from the human protein was used as the immunogen for this Progesterone Receptor antibody.

Isotyp: IgM, kappa

Anwendungsinformationen

Applikationshinweise: Titration of the Progesterone Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Progesterone Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Progesterone Receptor

Target: Progesterone Receptor (PGR)

Andere Bezeichnung: Progesterone Receptor

Hintergrund: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration