Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Tuberin Antikörper (pSer1387)

TSC2 Reaktivität: Human ELISA, DB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029322
  • Target Alle Tuberin (TSC2) Antikörper anzeigen
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    Bindungsspezifität
    • 34
    • 21
    • 19
    • 18
    • 16
    • 16
    • 15
    • 15
    • 15
    • 11
    • 10
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1387
    Reaktivität
    • 270
    • 180
    • 116
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 362
    • 12
    Kaninchen
    Klonalität
    • 352
    • 22
    Polyklonal
    Konjugat
    • 140
    • 31
    • 31
    • 29
    • 22
    • 21
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    Dieser Tuberin Antikörper ist unkonjugiert
    Applikation
    • 199
    • 168
    • 121
    • 81
    • 80
    • 62
    • 36
    • 32
    • 20
    • 12
    • 10
    • 7
    • 6
    • 5
    • 2
    ELISA, Dot Blot (DB), Immunofluorescence (IF)
    Kreuzreaktivität (Details)
    Expected species reactivity: Mouse, Rat
    Aufreinigung
    Antigen affinity purified
    Immunogen
    This phospho-TSC2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1387 of human TSC2.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TSC2 Primärantikörper
  • Applikationshinweise
    Titration of the phospho-TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500,Immunofluorescence: 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the phospho-TSC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    Andere Bezeichnung
    TSC2 (TSC2 Produkte)
    Hintergrund
    Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.
    UniProt
    P49815
    Pathways
    RTK Signalweg, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
Sie sind hier:
Kundenservice