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ATM Antikörper (pSer1981)

Dieses Anti-ATM-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ATM in ELISA, IF und DB. Geeignet für Human.
Produktnummer ABIN3030033

Kurzübersicht für ATM Antikörper (pSer1981) (ABIN3030033)

Target

Alle ATM Antikörper anzeigen
ATM (Ataxia Telangiectasia Mutated (ATM))

Reaktivität

  • 163
  • 73
  • 32
  • 2
  • 1
  • 1
Human

Wirt

  • 133
  • 26
  • 5
  • 2
Kaninchen

Klonalität

  • 123
  • 43
Polyklonal

Konjugat

  • 89
  • 8
  • 7
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
Dieser ATM Antikörper ist unkonjugiert

Applikation

  • 78
  • 52
  • 43
  • 39
  • 28
  • 28
  • 26
  • 25
  • 23
  • 18
  • 7
  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA, Immunofluorescence (IF), Dot Blot (DB)
  • Bindungsspezifität

    • 33
    • 16
    • 15
    • 13
    • 8
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1981

    Aufreinigung

    Antigen affinity purified

    Immunogen

    This phospho-ATM antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1981 of human ATM.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Titration of the phospho-ATM antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500,Immunofluorescence: 1:10-1:50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the phospho-ATM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    ATM (Ataxia Telangiectasia Mutated (ATM))

    Andere Bezeichnung

    ATM

    Hintergrund

    ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2,checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. ATM and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in the gene encoding ATM are associated with ataxia telangiectasia, an autosomal recessive disorder.

    UniProt

    Q13315

    Pathways

    p53 Signalweg, Apoptose, DNA Reparatur, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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