Expected species reactivity: Bovine, Chicken, Human, Rat, Xenopus, Zebrafish
Aufreinigung
Antigen affinity purified
Immunogen
This mouse Pax6 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 404-436 amino acids from the C-terminal region of mouse Pax6.
PAX6
Reaktivität: Human
WB, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Titration of the Pax6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Pax6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
PAX6
(Paired Box 6 (PAX6))
Andere Bezeichnung
Pax6
Hintergrund
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).