PARP1 Antikörper (AA 123-151)
Kurzübersicht für PARP1 Antikörper (AA 123-151) (ABIN3028937)
Target
Alle PARP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 123-151
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 123-151 from the human protein was used as the immunogen for this PARP1 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the PARP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the PARP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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Andere Bezeichnung
- PARP
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Hintergrund
- This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. It is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. [UniProt]
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UniProt
- P09874
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Target
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