PAK2 Antikörper (AA 192-222)
Kurzübersicht für PAK2 Antikörper (AA 192-222) (ABIN3032117)
Target
Alle PAK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 192-222
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Verwendungszweck
- PAK2 Antibody
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 192-222 from the human protein was used as the immunogen for this PAK2 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the PAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the PAK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PAK2 (P21-Activated Kinase 2 (PAK2))
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Andere Bezeichnung
- PAK2
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Hintergrund
- PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain.
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UniProt
- Q13177
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Pathways
- MAPK Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Lipid Metabolism by PPARalpha
Target
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