PARP1 Antikörper (pSer373)
Kurzübersicht für PARP1 Antikörper (pSer373) (ABIN3028936)
Target
Alle PARP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer373
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Verwendungszweck
- Phospho-PARP1 Antibody (pS373)
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Aufreinigung
- Antigen affinity purified
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Immunogen
- This Phospho-PARP1 (pS373) Antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS373 of rat PARP1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the Phospho-PARP1 (pS373) Antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Phospho-PARP1 (pS373) Antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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Andere Bezeichnung
- PARP
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Hintergrund
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Phospho-PARP1 (pS373) Antibody specifically detects PARP1 phosphorylated at the serine 373 site. Catalyzes poly (ADP-ribose) protein modification, plays a role in DNA repair and genome stability [RGD].
Phosphorylation-dependent PARP1 signaling studies may also benefit from our < a href=../tds/phospho-parp-antibody-ps177-f48726>phospho-PARP1 (Ser177) antibody page focused on DNA damage response and chromatin stress pathway regulation. -
UniProt
- P27008
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Target
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