NADPH Oxidase 4 Antikörper (AA 124-153)

Produktnummer ABIN3031934

Der Kaninchen Polyklonal Anti-NADPH Oxidase 4-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, NADPH Oxidase 4 in Proben von Human zu detektieren.

Kurzübersicht für NADPH Oxidase 4 Antikörper (AA 124-153) (ABIN3031934)

Target: NADPH Oxidase 4 (NOX4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-NADPH Oxidase 4 Antikörper

Bindungsspezifität: AA 124-153

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 124-153 from the human protein was used as the immunogen for this NOX4 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the NOX4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NOX4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Andere Bezeichnung: NOX4

Hintergrund: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration