NLRP6 Antikörper (AA 168-197)

Produktnummer ABIN3032023

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NLRP6 in ELISA und WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NLRP6 Antikörper (AA 168-197) (ABIN3032023)

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP6 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-NLRP6 Antikörper

Bindungsspezifität: AA 168-197

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 168-197 from the human protein was used as the immunogen for this NLRP6 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the NLRP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NLRP6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NLRP6

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Andere Bezeichnung: NLRP6

Hintergrund: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1, also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.

UniProt: P59044

Pathways: Inflammasome