NEUROD1 Antikörper (AA 318-348)
Kurzübersicht für NEUROD1 Antikörper (AA 318-348) (ABIN3031978)
Target
Alle NEUROD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 318-348
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Verwendungszweck
- NeuroD1 Antibody
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 318-348 from the human protein was used as the immunogen for this NeuroD1 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the NeuroD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the NeuroD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
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Andere Bezeichnung
- NeuroD1
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Hintergrund
- NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
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UniProt
- Q13562
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Pathways
- Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
Target
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