NEUROD1 Antikörper (AA 318-348)

Produktnummer ABIN3031978

Produktdetails anti-NEUROD1 Antikörper

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Bindungsspezifität: AA 318-348

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEUROD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Purified

Immunogen: A portion of amino acids 318-348 from the human protein was used as the immunogen for this NeuroD1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the NeuroD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NeuroD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NEUROD1

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Andere Bezeichnung: NeuroD1 (NEUROD1 Produkte)

Hintergrund: NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis