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MME Antikörper (AA 506-534)

Name: MME Antikörper (AA 506-534)
SKU: ABIN3031746
Price: 673.5 EUR
Availability: InStock

MME Reaktivität: Human FACS, WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of Neprilysin antibody and 1) A2058, 2) A375, 3) Ramos lysate. (MME Antikörper (AA 506-534))

IHC analysis of FFPE human kidney carcinoma with Neprilysin antibody (MME Antikörper (AA 506-534))

IHC

Neprilysin antibody flow cytometry analysis of Ramos cells (green) compared to a negative control (blue). (MME Antikörper (AA 506-534))

FACS

IHC

5 Abbildungen

Produktnummer ABIN3031746

Datenblatt (PDF)

Target Alle MME Antikörper anzeigen

MME (Membrane Metallo-Endopeptidase (MME))
Bindungsspezifität
10

9

8

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 506-534
Reaktivität
189

45

38

3

2

2

2

2

2

1

1

1

1
Human
Wirt
105

89

2
Kaninchen
Passende Sekundärantikörper
Klonalität
113

82

2
Polyklonal
Konjugat
109

17

16

11

7

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MME Antikörper ist unkonjugiert
Applikation
103

78

74

60

38

27

20

18

10

8

5

5

3

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität (Details)

Expected species reactivity: Mouse, Rat, Rabbit

Aufreinigung

Antigen affinity purified

Immunogen

A portion of amino acids 506-534 from the human protein was used as the immunogen for this Neprilysin antibody.

Isotyp

Ig Fraction

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Applikationshinweise

Titration of the Neprilysin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Aliquot the Neprilysin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target

MME (Membrane Metallo-Endopeptidase (MME))

Andere Bezeichnung

Neprilysin (MME Produkte)

Substanzklasse

Chemical

Hintergrund

MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

UniProt

P08473

Pathways

RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration