LDLR Antikörper (AA 391-419)

Produktnummer ABIN3031637

Der Kaninchen Polyklonal Anti-LDLR-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, LDLR in Proben von Human und Maus zu detektieren.

Kurzübersicht für LDLR Antikörper (AA 391-419) (ABIN3031637)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LDLR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-LDLR Antikörper

Bindungsspezifität: AA 391-419

Kreuzreaktivität (Details): Expected species reactivity: Rat, Pig, Rabbit, Hamster, Xenopus

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 391-419 from the human protein was used as the immunogen for this LDLR antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the LDLR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the LDLR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Andere Bezeichnung: LDLR

Hintergrund: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism