Insulin Receptor Antikörper (AA 21-52)
Kurzübersicht für Insulin Receptor Antikörper (AA 21-52) (ABIN3031335)
Target
Alle Insulin Receptor (INSR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 21-52
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 21-52 from the human protein was used as the immunogen for this Insulin Receptor antibody.
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Isotyp
- Ig Fraction
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anti-Insulin Receptor (INSR) antibody
INSR Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C7 unconjugated
anti-Insulin Receptor (INSR) (AA 1024-1298) antibodyINSR Reaktivität: Human WB, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1027-1364) antibodyINSR Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1101-1372) antibodyINSR Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyINSR Reaktivität: Human, Maus, Ratte, Hund, Affe, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Schwein, Huhn, Schaf, Hamster, Avian, Cat, Esel, Ziege WB Wirt: Ziege Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyKO Validated INSR Reaktivität: Human WB, ICC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1325-1358) antibodyINSR Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB50340 unconjugated
anti-Insulin Receptor (INSR) (AA 1023-1298) antibodyINSR Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 51-150) antibodyINSR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 27-57), (N-Term) antibodyINSR Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB1421 unconjugated
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Applikationshinweise
- Titration of the Insulin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Insulin Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Insulin Receptor (INSR)
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Andere Bezeichnung
- Insulin Receptor
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Hintergrund
- INSR binds insulin and has a tyrosine-protein kinase activity. Autophosphorylation activates the kinase activity. This Type I mebrane protein is composed of a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. After being transported from the endoplasmic reticulum to the Golgi apparatus, the single glycosylated precursor is further glycosylated and then cleaved, followed by its transport to the plasma membrane.
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UniProt
- P06213
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Target
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