IGF1R Antikörper (AA 19-51)
Kurzübersicht für IGF1R Antikörper (AA 19-51) (ABIN3031344)
Target
Alle IGF1R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 19-51
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Verwendungszweck
- IGF1R Antibody
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 19-51 from the human protein was used as the immunogen for this IGF1R antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the IGF1R antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the IGF1R antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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Andere Bezeichnung
- IGF1R
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Hintergrund
- The IGF1 receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
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UniProt
- P08069
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Pathways
- RTK Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagie
Target
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