HMGB2 Antikörper (AA 92-118)

Produktnummer ABIN3031202

Der Kaninchen Polyklonal Anti-HMGB2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, HMGB2 in Proben von Human zu detektieren.

Kurzübersicht für HMGB2 Antikörper (AA 92-118) (ABIN3031202)

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HMGB2 Antikörper

Bindungsspezifität: AA 92-118

Kreuzreaktivität (Details): Expected species reactivity: Rat, Bovine, Pig

Aufreinigung: Purified

Immunogen: A portion of amino acids 92-118 from the human protein was used as the immunogen for this HMGB2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the HMGB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the HMGB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu HMGB2

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Andere Bezeichnung: HMGB2

Hintergrund: HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

UniProt: P26583

Pathways: Cellular Response to Molecule of Bacterial Origin