GLI2 Antikörper (C-Term)

Produktnummer ABIN3031039

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GLI2 in WB, ELISA, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GLI2 Antikörper (C-Term) (ABIN3031039)

Target: GLI2 (GLI Family Zinc Finger 2 (GLI2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-GLI2 Antikörper

Bindungsspezifität: AA 1287-1321, C-Term

Verwendungszweck: GLI2 Antibody

Aufreinigung: Antigen affinity

Immunogen: This GLI2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1287-1321 amino acids from the C-terminal region of human GLI2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the GLI2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. GLI-2 exists as five alternatively spliced isoforms of 133 kDa (isoform 1), 132 (2), 88 (3), 86 (4) and 168 kDa (isoform 5).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the GLI2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu GLI2

Target: GLI2 (GLI Family Zinc Finger 2 (GLI2))

Andere Bezeichnung: GLI2

Hintergrund: Acts as a transcriptional activator. May play a role during embryogenesis. Binds to the DNA sequence 5'-GAACCACCCA-3' which is part of the TRE-2S regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1. Is involved in the smoothened (SHH) signaling pathway.

UniProt: P10070

Pathways: Hedgehog Signalweg, Dopaminergic Neurogenesis