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Cyclin D2 Antikörper (AA 1-30)

Der Kaninchen Polyklonal Anti-Cyclin D2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Cyclin D2 in Proben von Human zu detektieren.
Produktnummer ABIN3030593

Kurzübersicht für Cyclin D2 Antikörper (AA 1-30) (ABIN3030593)

Target

Alle Cyclin D2 (CCND2) Antikörper anzeigen
Cyclin D2 (CCND2)

Reaktivität

  • 97
  • 48
  • 37
Human

Wirt

  • 68
  • 33
Kaninchen

Klonalität

  • 71
  • 30
Polyklonal

Konjugat

  • 55
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Cyclin D2 Antikörper ist unkonjugiert

Applikation

  • 68
  • 37
  • 17
  • 15
  • 14
  • 13
  • 13
  • 11
  • 10
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 16
    • 12
    • 9
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-30

    Aufreinigung

    Antigen affinity purified

    Immunogen

    A portion of amino acids 1-30 from the human protein was used as the immunogen for this Cyclin D2 antibody.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Titration of the Cyclin D2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the Cyclin D2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    Cyclin D2 (CCND2)

    Hintergrund

    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.

    UniProt

    P30279

    Pathways

    Zellzyklus, Mitotic G1-G1/S Phases
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