Der Kaninchen Polyklonal Anti-CDK9-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CDK9 in Proben von Human, Maus und Ratte zu detektieren.
Titration of the Cdk9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Cdk9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
CDK9
(Cyclin-Dependent Kinase 9 (CDK9))
Andere Bezeichnung
Cdk9
Hintergrund
Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro (By similarity).