CDC25A Antikörper (N-Term)
Kurzübersicht für CDC25A Antikörper (N-Term) (ABIN3030441)
Target
Alle CDC25A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- Cdc25A Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- This Cdc25A antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Cdc25A.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the Cdc25A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Cdc25A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
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Andere Bezeichnung
- Cdc25A
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Hintergrund
- CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
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UniProt
- P30304
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, M Phase
Target
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