CD44 Antikörper (AA 688-722)
Kurzübersicht für CD44 Antikörper (AA 688-722) (ABIN3030400)
Target
Alle CD44 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 688-722
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Aufreinigung
- Antigen affinity purified
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Immunogen
- This CD44 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 688-722 amino acids from the C-terminal region of human CD44.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the CD44 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the CD44 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CD44
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Andere Bezeichnung
- CD44
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Hintergrund
- Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
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UniProt
- P16070
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Pathways
- Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling
Target
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