Cyclin D1 Antikörper (AA 267-294)
Kurzübersicht für Cyclin D1 Antikörper (AA 267-294) (ABIN3029708)
Target
Alle Cyclin D1 (CCND1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 267-294
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 267-294 from the human protein was used as the immunogen for this CCND1 antibody.
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Isotyp
- Ig Fraction
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anti-Cyclin D1 (CCND1) (AA 61-110) antibody
CCND1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schaf WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (AA 68-97) antibodyCCND1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB8066 unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D1 (CCND1) antibodyKO Validated CCND1 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Cyclin D1 (CCND1) (AA 167-295) antibodyCCND1 Reaktivität: Human IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 3B6G3 unconjugated
anti-Cyclin D1 (CCND1) (AA 1-295) antibodyCCND1 Reaktivität: Human, Maus WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 1F7F5 unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (AA 68-97) antibodyCCND1 Reaktivität: Human, Maus WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D1 (CCND1) antibodyCCND1 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, FACS, IF, StM Wirt: Maus Monoclonal DCS-6 unconjugated
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Applikationshinweise
- Titration of the CCND1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the CCND1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Cyclin D1 (CCND1)
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Hintergrund
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
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UniProt
- P24385
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Pathways
- PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
Target
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