KIT Antikörper (AA 106-135)

Produktnummer ABIN3031704

Dieses Anti-KIT-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KIT in WB, FACS, ELISA und IHC. Geeignet für Human und Maus.

Kurzübersicht für KIT Antikörper (AA 106-135) (ABIN3031704)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-KIT Antikörper

Bindungsspezifität: AA 106-135

Aufreinigung: Purified

Immunogen: A portion of amino acids 106-135 from the human protein was used as the immunogen for this c-Kit antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the c-Kit antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the c-Kit antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Andere Bezeichnung: C-Kit

Hintergrund: KIT is the human homolog of the proto-oncogene c-kit. c-Kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

UniProt: P10721

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity