BMI1 Antikörper (C-Term)
Kurzübersicht für BMI1 Antikörper (C-Term) (ABIN3030166)
Target
Alle BMI1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 230-265, C-Term
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Verwendungszweck
- BMI1 Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- This BMI1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 230-265 amino acids from the C-terminal region of human BMI1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the BMI1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the BMI1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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Andere Bezeichnung
- BMI1
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Hintergrund
- Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
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UniProt
- P35226
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Pathways
- Zellzyklus, Autophagie
Target
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